A coupling (or a coupler) is a mechanism for connecting rolling stock in a train. The design of the coupler is standard, and is almost as important as the track gauge, since flexibility and convenience are maximised if all rolling stock can be coupled together.
The company was founded by John Griffin in 1975.The company operates a fleet of 4,000 vehicles with annual revenues of over £200m. As well as being a private hire operator, Addison Lee also operates a private coach company with a fleet of 100 coaches of various sizes. The company carries out over 20,000 jobs every day.
An invention is a unique or noveldevice, method, composition or process. It may be an improvement upon a machine or product, or a new process for creating an object or a result. An invention that achieves a completely unique function or result may be a radical breakthrough. Such works are novel and not obvious to others skilled in the same field.
Zymosan is a glucan with repeating glucose units connected by β-1,3-glycosidic linkages. It binds to TLR 2. Zymosan is a ligand found on the surface of fungi, like yeast.